FOXO1

Across TCGA patient cohorts, FOXO1 protein abundance is significantly associated with the RNA expression of many other genes, with 9,667 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FOXO1-associated genes across cancer lineages are GALNT15, ABCA6, and TMEM119. Each is linked with FOXO1 in more than 5 cancer types. Because this analysis shows association rather than direction, both FOXO1-to-partner and partner-to-FOXO1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FOXO1 versus GALNT15 in BRCA, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXO1→partner) and Y-score (partner→FOXO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	GALNT15 →	+0.756	+0.332	<.001	<.001	3	6
UCEC	ABCA6 →	+0.825	+0.394	.001	.002	3	6
OV	TMEM119 →	+1.145	+0.296	<.001	<.001	3	6
UCEC	CNRIP1 →	+0.848	+0.292	<.001	<.001	3	6
UCEC	PDGFRA →	+0.939	+0.335	<.001	<.001	3	6
UCEC	FGF7 →	+1.058	+0.339	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,667 associations by consensus.

FOXO1 vs GALNT15 — BRCA

Explore this scatter interactively →