FOXN4

Across TCGA cell cohorts, FOXN4 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,779 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible FOXN4-associated GO terms across cancer lineages are Amacrine cell differentiation, Regulation of potassium ion transmembrane transport, and Positive regulation of DNA repair. Each is linked with FOXN4 in more than 11 cancer types. Because this analysis shows association rather than direction, both FOXN4-to-partner and partner-to-FOXN4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Amacrine cell differentiation grouped by FOXN4-low versus FOXN4-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXN4→partner) and Y-score (partner→FOXN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Amacrine cell differentiation →	+0.691	+1.428	.001	<.001	3	12
BLOOD_Lymphoma	Regulation of potassium ion transmembrane transport →	-0.070	-0.533	.002	.005	3	11
LUNG_SCLC	Positive regulation of DNA repair →	+0.077	+1.819	<.001	<.001	3	8
LUNG_SCLC	Nuclear-transcribed mRNA catabolic process →	+0.045	+1.645	.002	.001	3	8
BONE	Copper ion export →	-0.157	-1.546	.002	.006	3	8
BONE	Integrin-mediated signaling pathway →	-0.333	-1.152	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,779 associations by consensus.

Amacrine cell differentiation by FOXN4 expression — BONE

Explore this box plot interactively →