FOXN3

Across TCGA patient cohorts, FOXN3 protein abundance is significantly associated with the RNA expression of many other genes, with 4,022 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible FOXN3-associated genes across cancer lineages are RGL1, BDH2, and CAP2P1. Each is linked with FOXN3 in more than 1 cancer types. Because this analysis shows association rather than direction, both FOXN3-to-partner and partner-to-FOXN3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FOXN3 versus RGL1 in HNSC, with a Pearson correlation of 0.23.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXN3→partner) and Y-score (partner→FOXN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RGL1 →	+0.667	+0.448	.007	.006	3	2
LSCC	BDH2 →	+0.585	+0.294	<.001	.001	3	2
HNSC	CAP2P1 →	+0.768	+0.576	<.001	<.001	3	2
LUAD	MYOF →	-0.567	-0.218	.003	.005	3	2
LSCC	S100A10 →	-0.775	-0.196	.002	.002	3	2
UCEC	MFNG →	+1.268	+0.539	.005	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,022 associations by consensus.

FOXN3 vs RGL1 — HNSC

Explore this scatter interactively →