FOXN3

Across TCGA cell cohorts, FOXN3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,034 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FOXN3-associated GO terms across cancer lineages are Regulation of nucleotide-excision repair, Epigenetic regulation of gene expression, and Heterochromatin organization. Each is linked with FOXN3 in more than 13 cancer types. Because this analysis shows association rather than direction, both FOXN3-to-partner and partner-to-FOXN3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of nucleotide-excision repair grouped by FOXN3-low versus FOXN3-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXN3→partner) and Y-score (partner→FOXN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Regulation of nucleotide-excision repair →	+0.110	+2.564	.001	<.001	3	14
OVARY	Epigenetic regulation of gene expression →	+0.069	+1.324	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Heterochromatin organization →	+0.074	+1.379	<.001	.001	3	12
UPPER_AERODIGESTIVE_TRACT	Cytokinesis →	+0.064	+0.871	.002	.006	3	12
UPPER_AERODIGESTIVE_TRACT	Cytoskeleton-dependent cytokinesis →	+0.065	+0.862	.002	.006	3	12
STOMACH	Regulation of G1/S transition of mitotic cell cycle →	+0.078	+1.607	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,034 associations by consensus.

Regulation of nucleotide-excision repair by FOXN3 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →