Across TCGA patient cohorts, FOXL2 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,692 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FOXL2-associated proteins across cancer lineages are FOXL2_S33, SPATS2L_S159, and ANKRD13A. Each is linked with FOXL2 in more than 3 cancer types. Because this analysis shows association rather than direction, both FOXL2-to-partner and partner-to-FOXL2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXL2→partner) and Y-score (partner→FOXL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	FOXL2_S33 →	+1.750	+1.954	<.001	<.001	3	4
OV	SPATS2L_S159 →	-1.079	-0.591	<.001	.007	3	3
OV	ANKRD13A →	-0.279	-0.713	<.001	<.001	3	3
OV	TCEAL1 →	+0.441	+0.945	<.001	<.001	3	3
COAD	ACSL5 →	-0.419	-0.053	.002	.002	3	3
HNSC	ERRFI1_T127 →	+0.784	+1.863	.008	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,692 associations by consensus.

Exploration

FOXL2 survival (RNA) · tumor vs normal (RNA) · all FOXL2 data types