Across TCGA cell cohorts, FOXL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,785 significant associations in total. OESOPHAGUS shows the largest number of these associations.

The most reproducible FOXL2-associated GO terms across cancer lineages are Oocyte growth, Extraocular skeletal muscle development, and Apoptotic DNA fragmentation. Each is linked with FOXL2 in more than 15 cancer types. Because this analysis shows association rather than direction, both FOXL2-to-partner and partner-to-FOXL2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXL2→partner) and Y-score (partner→FOXL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Oocyte growth →	-0.248	-1.508	<.001	<.001	3	16
CNS	Extraocular skeletal muscle development →	+0.191	+0.983	.002	<.001	3	12
LUNG_NSCLC_LUSC	Apoptotic DNA fragmentation →	-0.060	-1.592	.006	<.001	3	7
OESOPHAGUS	Regulation of translational initiation →	+0.109	+1.560	<.001	.001	3	7
OESOPHAGUS	Regulation of post-translational protein modification →	+0.061	+1.442	.002	.001	3	7
STOMACH	Regulation of telomere maintenance →	+0.066	+1.102	<.001	.002	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,785 associations by consensus.

Exploration

FOXL2 survival (RNA) · tumor vs normal (RNA) · all FOXL2 data types