Across TCGA cell cohorts, FOXL2 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FOXL2-associated genes across cancer lineages are S100A7A, IFNL3, and KRTAP7-1. Each is linked with FOXL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FOXL2-to-partner and partner-to-FOXL2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXL2→partner) and Y-score (partner→FOXL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	S100A7A →	+0.056	+5.643	<.001	.002	3	1
BLOOD_Lymphoma	IFNL3 →	+0.100	+5.209	.001	.005	3	1
BLOOD_Lymphoma	KRTAP7-1 →	+0.031	+4.867	<.001	.009	3	1
BLOOD_Leukemia	C20orf85 →	+0.052	+6.554	<.001	<.001	3	1
BLOOD_Leukemia	IL22 →	+0.037	+5.569	<.001	.001	3	1
BLOOD_Leukemia	ART1 →	+0.022	+4.705	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

Exploration

FOXL2 survival (RNA) · tumor vs normal (RNA) · all FOXL2 data types