FOXJ2

Across TCGA patient cohorts, FOXJ2 protein abundance is significantly associated with the RNA expression of many other genes, with 10,589 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FOXJ2-associated genes across cancer lineages are FAM66C, EBF4, and NCAPD2. Each is linked with FOXJ2 in more than 3 cancer types. Because this analysis shows association rather than direction, both FOXJ2-to-partner and partner-to-FOXJ2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FOXJ2 versus FAM66C in LSCC, with a Pearson correlation of 0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXJ2→partner) and Y-score (partner→FOXJ2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	FAM66C →	+0.850	+0.348	<.001	<.001	3	3
BRCA	EBF4 →	+0.989	+0.267	<.001	.008	3	3
HNSC	NCAPD2 →	+0.676	+0.377	.007	<.001	3	3
GBM	CDCA3 →	+0.622	+0.345	<.001	<.001	3	3
GBM	TRAPPC2LP1 →	+0.670	+0.294	<.001	.001	3	3
LSCC	DDX47 →	+0.449	+0.317	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,589 associations by consensus.

FOXJ2 vs FAM66C — LSCC

Explore this scatter interactively →