FOXJ2

Across TCGA cell cohorts, FOXJ2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,838 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FOXJ2-associated GO terms across cancer lineages are Negative regulation of DNA-templated transcription initiation, Negative regulation of transcription initiation by RNA polymerase II, and Cytosolic transport. Each is linked with FOXJ2 in more than 13 cancer types. Because this analysis shows association rather than direction, both FOXJ2-to-partner and partner-to-FOXJ2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of DNA-templated transcription initiation grouped by FOXJ2-low versus FOXJ2-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXJ2→partner) and Y-score (partner→FOXJ2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Negative regulation of DNA-templated transcription initiation →	+0.101	+0.671	.002	.002	3	14
LARGE_INTESTINE	Negative regulation of transcription initiation by RNA polymerase II →	+0.101	+0.671	.002	.002	3	14
BONE	Cytosolic transport →	+0.076	+0.646	<.001	.003	3	13
BONE	Negative regulation of organelle assembly →	+0.069	+0.665	<.001	<.001	3	13
PANCREAS	Positive regulation of mitotic cytokinesis →	+0.123	+0.642	<.001	<.001	3	13
STOMACH	Process utilizing autophagic mechanism →	+0.078	+0.952	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,838 associations by consensus.

Negative regulation of DNA-templated transcription initiation by FOXJ2 expression — LARGE_INTESTINE

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