Across TCGA patient cohorts, FOXI3 protein abundance is significantly associated with the RNA expression of many other genes, with 1,533 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FOXI3-associated genes across cancer lineages are SPECC1L, SNRPD3, and PES1. Each is linked with FOXI3 in more than 1 cancer types. Because this analysis shows association rather than direction, both FOXI3-to-partner and partner-to-FOXI3 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXI3→partner) and Y-score (partner→FOXI3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SPECC1L →	+0.834	+1.789	.004	.003	3	1
LSCC	SNRPD3 →	+0.902	+1.341	.005	.002	3	1
LSCC	PES1 →	+1.267	+1.507	.002	.003	3	1
LSCC	MAPK1 →	+0.919	+1.215	.001	.007	3	1
LSCC	MFNG →	-1.013	-1.195	.006	.009	3	1
LSCC	TFIP11 →	+0.787	+1.113	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,533 associations by consensus.

Exploration

FOXI3 survival (RNA) · tumor vs normal (RNA) · all FOXI3 data types