Across TCGA patient cohorts, FOXI2 mutation is significantly associated with the RNA expression of many other genes, with 1,606 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FOXI2-associated genes across cancer lineages are TRIM64B, RNA5SP259, and RPL5P19. Each is linked with FOXI2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FOXI2-to-partner and partner-to-FOXI2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXI2→partner) and Y-score (partner→FOXI2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	TRIM64B →	+0.322	+5.418	<.001	.005	3	2
CESC	RNA5SP259 →	+0.397	+5.103	<.001	.008	3	2
CESC	RPL5P19 →	+0.107	+6.144	<.001	.001	3	2
CESC	TRIM64EP →	+0.075	+5.969	<.001	.002	3	2
COAD	TRGJP1 →	+0.655	+3.754	.006	.008	3	2
COAD	LINC02620 →	+0.488	+3.754	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,606 associations by consensus.

Exploration

FOXI2 survival (RNA) · tumor vs normal (RNA) · all FOXI2 data types