Across TCGA cell cohorts, FOXI2 RNA expression is significantly associated with the mutation status of many other genes, with 125 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible FOXI2-associated genes across cancer lineages are SH3RF1, BICRA, and RFX7. Each is linked with FOXI2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FOXI2-to-partner and partner-to-FOXI2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXI2→partner) and Y-score (partner→FOXI2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	SH3RF1 →	+4.930	+0.006	.008	<.001	3	2
BONE	BICRA →	+4.169	+0.042	.008	.001	3	2
LUNG_SCLC	RFX7 →	+4.058	+0.046	.001	<.001	3	2
CNS	NPAT →	+4.321	+0.009	.009	<.001	3	2
SKIN	TGFB2 →	+4.684	+0.006	.002	<.001	3	2
BLOOD_Lymphoma	ITGAV →	+4.643	+0.284	.005	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 125 associations by consensus.

Exploration

FOXI2 survival (RNA) · tumor vs normal (RNA) · all FOXI2 data types