FOXI1

Across TCGA patient cohorts, FOXI1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,609 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible FOXI1-associated GO terms across cancer lineages are Regulation of miRNA metabolic process, Cellular response to sodium arsenite, and Sphingolipid metabolic process. Each is linked with FOXI1 in more than 8 cancer types. Because this analysis shows association rather than direction, both FOXI1-to-partner and partner-to-FOXI1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of miRNA metabolic process grouped by FOXI1-low versus FOXI1-high in LAML.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXI1→partner) and Y-score (partner→FOXI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LAML	Regulation of miRNA metabolic process →	+0.049	+0.220	<.001	<.001	3	9
LAML	Cellular response to sodium arsenite →	+0.057	+0.279	<.001	.001	3	9
THYM	Sphingolipid metabolic process →	+0.021	+1.352	<.001	.001	3	8
BLCA	Substantia nigra development →	+0.021	+0.443	<.001	<.001	3	8
LUSC	Obsolete ubiquitin-dependent ERAD pathway →	+0.026	+0.561	<.001	<.001	3	8
TGCT	Establishment or maintenance of cytoskeleton polarity →	+0.073	+0.350	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,609 associations by consensus.

Regulation of miRNA metabolic process by FOXI1 expression — LAML

Explore this box plot interactively →