FOXI1

Across TCGA cell cohorts, FOXI1 RNA expression is significantly associated with the go_rna of many other GO terms, with 394 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible FOXI1-associated GO terms across cancer lineages are Regulation of mRNA processing, Proteasomal ubiquitin-independent protein catabolic process, and Negative regulation of autophagy. Each is linked with FOXI1 in more than 4 cancer types. Because this analysis shows association rather than direction, both FOXI1-to-partner and partner-to-FOXI1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mRNA processing grouped by FOXI1-low versus FOXI1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXI1→partner) and Y-score (partner→FOXI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Regulation of mRNA processing →	+0.056	+1.558	.007	.002	3	5
STOMACH	Proteasomal ubiquitin-independent protein catabolic process →	+0.086	+0.210	<.001	.007	3	5
STOMACH	Negative regulation of autophagy →	+0.078	+0.372	.002	.007	3	5
BREAST	Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay →	+0.063	+1.505	.002	.003	3	5
BREAST	Cytoplasmic translation →	+0.066	+1.820	.009	.004	3	5
STOMACH	Protein polyubiquitination →	+0.048	+0.217	<.001	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 394 associations by consensus.

Regulation of mRNA processing by FOXI1 expression — BREAST

Explore this box plot interactively →