FOXG1

Across TCGA cell cohorts, FOXG1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,399 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible FOXG1-associated GO terms across cancer lineages are Positive regulation of proteasomal protein catabolic process, Negative regulation of microtubule depolymerization, and Cellular response to estrogen stimulus. Each is linked with FOXG1 in more than 4 cancer types. Because this analysis shows association rather than direction, both FOXG1-to-partner and partner-to-FOXG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of proteasomal protein catabolic process grouped by FOXG1-low versus FOXG1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXG1→partner) and Y-score (partner→FOXG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Positive regulation of proteasomal protein catabolic process →	+0.075	+1.422	.003	.001	3	5
SOFT_TISSUE	Negative regulation of microtubule depolymerization →	+0.073	+1.756	.003	.001	3	4
BREAST	Cellular response to estrogen stimulus →	-0.106	-0.481	<.001	.004	3	4
OVARY	Negative regulation of adaptive immune response →	-0.065	-1.858	<.001	.001	3	4
LUNG_NSCLC_LUAD	Regulation of microtubule depolymerization →	+0.048	+1.018	.006	<.001	3	4
OESOPHAGUS	Regulation of neurotransmitter secretion →	-0.088	-1.221	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,399 associations by consensus.

Positive regulation of proteasomal protein catabolic process by FOXG1 expression — OESOPHAGUS

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