FOXF2

Across TCGA patient cohorts, FOXF2 protein abundance is significantly associated with the RNA expression of many other genes, with 1,545 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible FOXF2-associated genes across cancer lineages are ATP6V1D, TMED8, and PPM1A. Each is linked with FOXF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FOXF2-to-partner and partner-to-FOXF2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FOXF2 versus ATP6V1D in PDAC, with a Pearson correlation of -0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXF2→partner) and Y-score (partner→FOXF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	ATP6V1D →	-0.597	-0.629	.004	.009	3	1
PDAC	TMED8 →	-0.458	-0.540	<.001	.001	3	1
PDAC	PPM1A →	-0.544	-0.539	<.001	<.001	3	1
PDAC	ZC3H14 →	-0.477	-0.540	.001	.003	3	1
PDAC	FERMT1 →	-1.111	-0.438	.002	.002	3	1
PDAC	NKAP →	-0.447	-0.686	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,545 associations by consensus.

FOXF2 vs ATP6V1D — PDAC

Explore this scatter interactively →