FOXF2

Across TCGA cell cohorts, FOXF2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,645 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible FOXF2-associated GO terms across cancer lineages are Nucleocytoplasmic transport, RNA export from nucleus, and Response to Gram-positive bacterium. Each is linked with FOXF2 in more than 7 cancer types. Because this analysis shows association rather than direction, both FOXF2-to-partner and partner-to-FOXF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleocytoplasmic transport grouped by FOXF2-low versus FOXF2-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXF2→partner) and Y-score (partner→FOXF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Nucleocytoplasmic transport →	+0.064	+1.941	.004	.002	3	8
OESOPHAGUS	RNA export from nucleus →	+0.110	+2.131	.001	<.001	3	7
LUNG_SCLC	Response to Gram-positive bacterium →	-0.220	-0.671	.004	.002	3	7
BREAST	Response to ionizing radiation →	+0.062	+1.725	<.001	<.001	3	7
BREAST	Establishment of apical/basal cell polarity →	+0.148	+1.678	<.001	<.001	2	8
OESOPHAGUS	Nuclear transport →	+0.062	+1.700	.005	.002	2	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,645 associations by consensus.

Nucleocytoplasmic transport by FOXF2 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →