FOXF2

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, FOXF2 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FOXF2-associated genes across cancer lineages are OR4F21. Each is linked with FOXF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FOXF2-to-partner and partner-to-FOXF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR4F21 grouped by FOXF2-low versus FOXF2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXF2→partner) and Y-score (partner→FOXF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEOR4F21 →+0.187+3.878<.001.00331
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

OR4F21 by FOXF2 expression — LARGE_INTESTINE

Box plot of OR4F21 in FOXF2-low vs FOXF2-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration