FOXF1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FOXF1 protein abundance is significantly associated with the RNA expression of many other genes, with 3,815 significant associations in total. COAD shows the largest number of these associations.

The most reproducible FOXF1-associated genes across cancer lineages are TRPC6, BDKRB1, and CTSZ. Each is linked with FOXF1 in more than 2 cancer types. Because this analysis shows association rather than direction, both FOXF1-to-partner and partner-to-FOXF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FOXF1 versus TRPC6 in GBM, with a Pearson correlation of 0.75.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXF1→partner) and Y-score (partner→FOXF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMTRPC6 →+1.447+2.411.007.00133
GBMBDKRB1 →+0.217+1.551.003.00332
GBMCTSZ →+1.383+1.551.001.00332
GBMMYL9 →+1.726+2.085.002.00532
GBMTIMP1 →+3.335+2.499<.001<.00132
GBMSERPINE1 →+2.738+1.851<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,815 associations by consensus.

FOXF1 vs TRPC6 — GBM

Per-sample scatter of FOXF1 vs TRPC6 in GBM (Pearson r = 0.75).

Explore this scatter interactively →

Exploration