FOXF1

Across TCGA patient cohorts, FOXF1 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible FOXF1-associated genes across cancer lineages are CD4+ Tcm, Eosinophils, and GMP. Each is linked with FOXF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FOXF1-to-partner and partner-to-FOXF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD4+ Tcm grouped by FOXF1-low versus FOXF1-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXF1→partner) and Y-score (partner→FOXF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CD4+ Tcm →	+0.023	+3.481	<.001	.023	3	1
LUSC	Eosinophils →	+0.040	+3.173	.004	.049	3	1
LUSC	GMP →	+0.046	+3.264	.012	.046	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

CD4+ Tcm by FOXF1 expression — LUAD

Explore this box plot interactively →