FOXF1

Across TCGA cell cohorts, FOXF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,852 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible FOXF1-associated GO terms across cancer lineages are Negative regulation of endodermal cell differentiation, Collagen biosynthetic process, and Collagen fibril organization. Each is linked with FOXF1 in more than 7 cancer types. Because this analysis shows association rather than direction, both FOXF1-to-partner and partner-to-FOXF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of endodermal cell differentiation grouped by FOXF1-low versus FOXF1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXF1→partner) and Y-score (partner→FOXF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Negative regulation of endodermal cell differentiation →	+1.290	+0.729	<.001	.003	3	8
LIVER	Collagen biosynthetic process →	+0.253	+2.070	<.001	<.001	3	8
LIVER	Collagen fibril organization →	+0.344	+1.852	<.001	.004	3	6
STOMACH	Embryonic digestive tract morphogenesis →	-0.281	-0.932	.006	.002	3	6
STOMACH	Regulation of establishment of protein localization to telomere →	+0.093	+0.832	<.001	.008	3	6
BONE	Positive regulation of cell-substrate junction organization →	+0.159	+1.174	<.001	.007	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,852 associations by consensus.

Negative regulation of endodermal cell differentiation by FOXF1 expression — OESOPHAGUS

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