FOXF1

Across TCGA cell cohorts, FOXF1 mutation is significantly associated with the RNA expression of many other genes, with 303 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FOXF1-associated genes across cancer lineages are CBY1, CDH20, and ASPN. Each is linked with FOXF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FOXF1-to-partner and partner-to-FOXF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CBY1 grouped by FOXF1-low versus FOXF1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXF1→partner) and Y-score (partner→FOXF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CBY1 →	+0.787	+3.299	<.001	.004	3	1
LARGE_INTESTINE	CDH20 →	+0.080	+2.667	.002	.002	3	1
LARGE_INTESTINE	ASPN →	+0.037	+2.841	<.001	.002	3	1
LARGE_INTESTINE	C6orf118 →	+0.087	+2.378	.001	.006	3	1
LARGE_INTESTINE	TXNDC15 →	+0.625	+3.212	.003	.006	3	1
LARGE_INTESTINE	WRAP73 →	+0.604	+3.212	.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 303 associations by consensus.

CBY1 by FOXF1 expression — LARGE_INTESTINE

Explore this box plot interactively →