FOXE1

Across TCGA patient cohorts, FOXE1 protein abundance is significantly associated with the RNA expression of many other genes, with 6,981 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FOXE1-associated genes across cancer lineages are CRYBB3, TCF20, and TTLL12. Each is linked with FOXE1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FOXE1-to-partner and partner-to-FOXE1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FOXE1 versus CRYBB3 in LSCC, with a Pearson correlation of 0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXE1→partner) and Y-score (partner→FOXE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CRYBB3 →	+0.864	+0.740	<.001	<.001	3	2
LSCC	TCF20 →	+0.646	+1.023	<.001	<.001	3	2
LSCC	TTLL12 →	+0.672	+0.618	<.001	<.001	3	2
LSCC	ACO2 →	+0.342	+0.823	.007	.004	3	2
HNSC	DESI1 →	+0.320	+0.527	.002	<.001	3	2
LSCC	ABHD4 →	+0.840	+0.731	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,981 associations by consensus.

FOXE1 vs CRYBB3 — LSCC

Explore this scatter interactively →