FOXD4L6

Across TCGA patient cohorts, FOXD4L6 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,185 significant associations in total. STAD shows the largest number of these associations.

The most reproducible FOXD4L6-associated GO terms across cancer lineages are Protein deacetylation, Negative regulation of RNA splicing, and Protein localization to mitochondrion. Each is linked with FOXD4L6 in more than 17 cancer types. Because this analysis shows association rather than direction, both FOXD4L6-to-partner and partner-to-FOXD4L6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein deacetylation grouped by FOXD4L6-low versus FOXD4L6-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXD4L6→partner) and Y-score (partner→FOXD4L6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Protein deacetylation →	+0.048	+0.030	<.001	<.001	3	18
STAD	Negative regulation of RNA splicing →	+0.064	+0.034	<.001	<.001	2	18
ESCA	Protein localization to mitochondrion →	+0.053	+0.053	.004	<.001	3	17
STAD	Establishment of protein localization to mitochondrial membrane →	+0.062	+0.032	<.001	<.001	3	16
STAD	Macromolecule deacylation →	+0.051	+0.029	<.001	<.001	3	16
SCLC	Positive regulation of DNA repair →	+0.054	+0.134	.009	.004	1	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,185 associations by consensus.

Protein deacetylation by FOXD4L6 expression — STAD

Explore this box plot interactively →