Across TCGA pan-cancer cohorts, FOXD4L4 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated FOXD4L4 data layer compared with 21 for mass-spec protein.

The strongest signal is observed in sarcoma (SARC), where higher FOXD4L4 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated FOXD4L4 expression acts as an unfavorable survival marker.

SARC are the cancer types where FOXD4L4 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SARC	DFS	Median	All	0.063	0.596	<.001	11	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

Exploration

Same gene, other analysis: FOXD4L4 tumor-vs-normal RNA expression · all FOXD4L4 data types