Across TCGA patient cohorts, FOXD4L4 mutation is significantly associated with the RNA expression of many other genes, with 222 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FOXD4L4-associated genes across cancer lineages are RPL26P34, RN7SL635P, and PAICSP6. Each is linked with FOXD4L4 in more than 1 cancer types. Because this analysis shows association rather than direction, both FOXD4L4-to-partner and partner-to-FOXD4L4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXD4L4→partner) and Y-score (partner→FOXD4L4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RPL26P34 →	+0.297	+5.017	<.001	.009	3	2
UCEC	RN7SL635P →	+0.217	+2.678	<.001	.003	3	2
SKCM	PAICSP6 →	+0.035	+3.809	<.001	.003	3	1
SKCM	ACTG1P13 →	+0.053	+3.508	<.001	.006	3	1
SKCM	MTCO2P9 →	+0.045	+5.163	<.001	.002	3	1
UCEC	MIR7702 →	+0.309	+4.738	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 222 associations by consensus.

Exploration

FOXD4L4 survival (RNA) · tumor vs normal (RNA) · all FOXD4L4 data types