FOXD4L4

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FOXD4L4 mutation is significantly associated with the total protein of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FOXD4L4-associated genes across cancer lineages are GSK-3a-b_pS21_S9 and TIGAR. Each is linked with FOXD4L4 in more than 1 cancer types. Because this analysis shows association rather than direction, both FOXD4L4-to-partner and partner-to-FOXD4L4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXD4L4→partner) and Y-score (partner→FOXD4L4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECGSK-3a-b_pS21_S9 →+0.603+2.817.021.03631
UCECTIGAR →+0.193+2.833.038.03521
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Exploration