Across TCGA patient cohorts, FOXD4L3 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,675 significant associations in total. STAD shows the largest number of these associations.

The most reproducible FOXD4L3-associated GO terms across cancer lineages are Facultative heterochromatin formation, Positive regulation of DNA-templated transcription, elongation, and Epigenetic regulation of gene expression. Each is linked with FOXD4L3 in more than 20 cancer types. Because this analysis shows association rather than direction, both FOXD4L3-to-partner and partner-to-FOXD4L3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXD4L3→partner) and Y-score (partner→FOXD4L3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Facultative heterochromatin formation →	+0.099	+0.133	.001	.005	2	21
STAD	Positive regulation of DNA-templated transcription, elongation →	+0.066	+0.070	<.001	<.001	3	20
SCLC	Epigenetic regulation of gene expression →	+0.071	+0.124	<.001	<.001	3	20
SCLC	Regulation of mRNA splicing, via spliceosome →	+0.072	+0.125	.001	.003	2	21
SCLC	Positive regulation of DNA metabolic process →	+0.046	+0.139	.004	.005	1	21
SCLC	Protein-RNA complex organization →	+0.088	+0.085	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,675 associations by consensus.

Exploration

FOXD4L3 survival (RNA) · tumor vs normal (RNA) · all FOXD4L3 data types