FOXD4L1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FOXD4L1 mutation is significantly associated with the RNA expression of many other genes, with 2,207 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FOXD4L1-associated genes across cancer lineages are LMNA, ZFPL1, and LZIC. Each is linked with FOXD4L1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FOXD4L1-to-partner and partner-to-FOXD4L1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXD4L1→partner) and Y-score (partner→FOXD4L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECLMNA →+0.412+2.807.006.00332
UCECZFPL1 →+0.464+2.931.001<.00132
UCECLZIC →+0.467+2.455.006.00132
UCECCCDC74A →-1.017-2.313<.001.00632
UCECC1orf50 →+0.310+3.616.001.00132
UCECRRP12 →+0.380+2.708.004.00332
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,207 associations by consensus.

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