FOXD4

Across TCGA cell cohorts, FOXD4 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,267 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible FOXD4-associated GO terms across cancer lineages are Flagellated sperm motility, Protein localization to cytoplasmic stress granule, and Lymphocyte mediated immunity. Each is linked with FOXD4 in more than 6 cancer types. Because this analysis shows association rather than direction, both FOXD4-to-partner and partner-to-FOXD4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Flagellated sperm motility grouped by FOXD4-low versus FOXD4-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXD4→partner) and Y-score (partner→FOXD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Flagellated sperm motility →	-0.126	-0.320	<.001	.003	3	7
SOFT_TISSUE	Protein localization to cytoplasmic stress granule →	+0.080	+0.671	.004	.004	3	7
PANCREAS	Lymphocyte mediated immunity →	-0.059	-0.279	.002	.005	3	7
UPPER_AERODIGESTIVE_TRACT	Cilium movement involved in cell motility →	-0.091	-0.260	.004	.005	3	7
UPPER_AERODIGESTIVE_TRACT	Sperm motility →	-0.126	-0.320	<.001	.003	3	7
UPPER_AERODIGESTIVE_TRACT	Cilium or flagellum-dependent cell motility →	-0.121	-0.290	<.001	.004	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,267 associations by consensus.

Flagellated sperm motility by FOXD4 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →