Across TCGA patient cohorts, FOXD2 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,069 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible FOXD2-associated proteins across cancer lineages are PPIB, HDLBP, and HSPA5. Each is linked with FOXD2 in more than 3 cancer types. Because this analysis shows association rather than direction, both FOXD2-to-partner and partner-to-FOXD2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXD2→partner) and Y-score (partner→FOXD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PPIB →	-0.331	-0.397	<.001	.001	3	4
LSCC	HDLBP →	-0.373	-0.538	<.001	<.001	3	4
COAD	HSPA5 →	-0.277	-0.672	.002	.006	3	4
BRCA	YBX3 →	-0.397	-0.594	.003	<.001	3	4
COAD	IVNS1ABP →	-0.385	-0.767	<.001	<.001	3	3
BRCA	PRDX4 →	-0.403	-0.544	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,069 associations by consensus.

Exploration

FOXD2 survival (RNA) · tumor vs normal (RNA) · all FOXD2 data types