FOXD2-AS1

Across TCGA pan-cancer cohorts, FOXD2-AS1 RNA is linked to patient survival in 29 of 34 cancer types, making it the most broadly survival-associated FOXD2-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher FOXD2-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated FOXD2-AS1 expression acts as an unfavorable survival marker, although some lineages such as OV and READ show a favorable association.

KIRC, KIRP, and ACC are the cancer types where FOXD2-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Quartile	All	0.541	0.739	<.001	148	view →
KIRP	OS	Median	All	0.602	0.760	<.001	128	view →
ACC	DFS	Median	All	0.261	0.619	<.001	98	view →
LIHC	DFS	Tertile	All	0.436	0.625	<.001	71	view →
KICH	DFS	Tertile	All	0.709	1.000	.004	57	view →
LGG	DFS	Median	All	0.657	0.824	<.001	54	view →
HNSC	OS	Tertile	All	0.498	0.767	.003	48	view →
CHOL	OS	Median	All	0.355	0.927	<.001	34	view →
THCA	DFS	Tertile	All	0.717	0.896	.001	31	view →
MESO	OS	Median	All	0.307	0.465	.017	27	view →
OV	DFS	Quartile	III,IV	0.456	0.323	.001	26	view →
READ	OS	Tertile	II,III,IV	0.960	0.683	.014	25	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 29 lineages.

FOXD2-AS1–KIRC (DFS)

Open the KIRC breakdown →