FOXCUT

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FOXCUT RNA expression is significantly associated with the protein abundance of many other proteins, with 9,814 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible FOXCUT-associated proteins across cancer lineages are WRNIP1, EXOC6, and PLEKHG1. Each is linked with FOXCUT in more than 4 cancer types. Because this analysis shows association rather than direction, both FOXCUT-to-partner and partner-to-FOXCUT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FOXCUT versus WRNIP1 in BRCA, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXCUT→partner) and Y-score (partner→FOXCUT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAWRNIP1 →+0.294+1.274.002<.00125
BRCAEXOC6 →-0.394-1.362<.001<.00133
BRCAPLEKHG1 →+0.442+0.901<.001<.00133
OVARPP19 →-0.469-0.589.002.00133
BRCAGLIPR2 →+0.581+1.848<.001<.00133
UCECMATN2 →+0.651+0.693.009.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 9,814 associations by consensus.

FOXCUT vs WRNIP1 — BRCA

Per-sample scatter of FOXCUT vs WRNIP1 in BRCA (Pearson r = 0.40).

Explore this scatter interactively →

Exploration