FOXC1

Across TCGA patient cohorts, FOXC1 protein abundance is significantly associated with the RNA expression of many other genes, with 2,612 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible FOXC1-associated genes across cancer lineages are CA6, PRSS12, and MBP. Each is linked with FOXC1 in more than 2 cancer types. Because this analysis shows association rather than direction, both FOXC1-to-partner and partner-to-FOXC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FOXC1 versus CA6 in BRCA, with a Pearson correlation of 0.24.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXC1→partner) and Y-score (partner→FOXC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CA6 →	+0.733	+0.477	.007	<.001	3	2
OV	PRSS12 →	+3.068	+1.605	<.001	<.001	3	2
OV	MBP →	+1.052	+1.160	<.001	<.001	3	2
OV	NPIPA3 →	-0.175	-1.062	.003	.005	3	2
BRCA	RDH10 →	+1.624	+0.532	<.001	.001	3	2
BRCA	GSDMC →	+1.376	+0.427	.002	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,612 associations by consensus.

FOXC1 vs CA6 — BRCA

Explore this scatter interactively →