FOXC1

Across TCGA cell cohorts, FOXC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,124 significant associations in total. BONE shows the largest number of these associations.

The most reproducible FOXC1-associated GO terms across cancer lineages are Regulation of lymphangiogenesis, Mesenchymal cell development, and Regulation of actin filament length. Each is linked with FOXC1 in more than 14 cancer types. Because this analysis shows association rather than direction, both FOXC1-to-partner and partner-to-FOXC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of lymphangiogenesis grouped by FOXC1-low versus FOXC1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXC1→partner) and Y-score (partner→FOXC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Regulation of lymphangiogenesis →	+1.609	+2.799	<.001	<.001	3	15
KIDNEY	Mesenchymal cell development →	+1.454	+1.187	<.001	.008	2	11
PANCREAS	Regulation of actin filament length →	+0.096	+1.491	<.001	<.001	3	8
URINARY_TRACT	Negative regulation of transforming growth factor beta production →	+0.312	+2.128	<.001	<.001	3	8
PANCREAS	Regulation of actin polymerization or depolymerization →	+0.097	+1.393	<.001	<.001	3	8
BONE	Schwann cell differentiation →	+0.119	+1.570	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,124 associations by consensus.

Regulation of lymphangiogenesis by FOXC1 expression — STOMACH

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