FOXB1

Across TCGA patient cohorts, FOXB1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,866 significant associations in total. STAD shows the largest number of these associations.

The most reproducible FOXB1-associated GO terms across cancer lineages are Positive regulation of leukocyte cell-cell adhesion, Activated T cell proliferation, and Interleukin-10 production. Each is linked with FOXB1 in more than 14 cancer types. Because this analysis shows association rather than direction, both FOXB1-to-partner and partner-to-FOXB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of leukocyte cell-cell adhesion grouped by FOXB1-low versus FOXB1-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXB1→partner) and Y-score (partner→FOXB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Positive regulation of leukocyte cell-cell adhesion →	+0.091	+0.318	<.001	<.001	3	15
ESCA	Activated T cell proliferation →	+0.058	+0.237	<.001	<.001	3	15
STAD	Interleukin-10 production →	+0.060	+0.105	<.001	<.001	3	15
ESCA	Positive regulation of hemopoiesis →	+0.085	+0.237	<.001	<.001	3	14
ESCA	Regulation of lymphocyte differentiation →	+0.082	+0.343	<.001	<.001	3	14
ESCA	Negative regulation of lymphocyte differentiation →	+0.084	+0.272	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,866 associations by consensus.

Positive regulation of leukocyte cell-cell adhesion by FOXB1 expression — ESCA

Explore this box plot interactively →