FOXA3

Across TCGA patient cohorts, FOXA3 protein abundance is significantly associated with the RNA expression of many other genes, with 934 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible FOXA3-associated genes across cancer lineages are DMXL2, ANGPTL3, and SOCS6P1. Each is linked with FOXA3 in more than 1 cancer types. Because this analysis shows association rather than direction, both FOXA3-to-partner and partner-to-FOXA3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FOXA3 versus DMXL2 in LUAD, with a Pearson correlation of -0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXA3→partner) and Y-score (partner→FOXA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	DMXL2 →	-0.956	-1.069	<.001	.007	3	1
LUAD	ANGPTL3 →	-0.715	-1.118	.002	.005	3	1
LUAD	SOCS6P1 →	-0.204	-0.753	<.001	.002	3	1
LUAD	RNU6-1267P →	-1.309	-0.880	.009	.006	3	1
LUAD	GSTA1 →	+4.732	+1.335	<.001	.005	3	1
LUAD	SPG21 →	-0.500	-0.794	.002	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 934 associations by consensus.

FOXA3 vs DMXL2 — LUAD

Explore this scatter interactively →