FOXA3

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, FOXA3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,129 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FOXA3-associated GO terms across cancer lineages are Response to copper ion, Renal D-glucose absorption, and Positive regulation of calcium ion import. Each is linked with FOXA3 in more than 6 cancer types. Because this analysis shows association rather than direction, both FOXA3-to-partner and partner-to-FOXA3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to copper ion grouped by FOXA3-low versus FOXA3-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXA3→partner) and Y-score (partner→FOXA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STOMACHResponse to copper ion →-0.151-2.532.001.00137
LIVERRenal D-glucose absorption →+1.772+3.113<.001<.00136
LARGE_INTESTINEPositive regulation of calcium ion import →-0.110-1.485.004.00436
LARGE_INTESTINEAcyl-CoA metabolic process →+0.062+1.448<.001<.00135
STOMACHNeurotransmitter receptor transport to plasma membrane →+0.177+2.142<.001.00235
STOMACHNeurotransmitter receptor transport to postsynaptic membrane →+0.177+2.142<.001.00235
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,129 associations by consensus.

Response to copper ion by FOXA3 expression — STOMACH

Box plot of Response to copper ion in FOXA3-low vs FOXA3-high samples in STOMACH.

Explore this box plot interactively →

Exploration