FOXA1

Across TCGA patient cohorts, FOXA1 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,533 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible FOXA1-associated proteins across cancer lineages are FOXA1_S331, CEACAM5, and TSPAN13. Each is linked with FOXA1 in more than 7 cancer types. Because this analysis shows association rather than direction, both FOXA1-to-partner and partner-to-FOXA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FOXA1 versus FOXA1_S331 in OV, with a Pearson correlation of 0.77.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXA1→partner) and Y-score (partner→FOXA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	FOXA1_S331 →	+2.367	+1.319	<.001	<.001	3	8
LSCC	CEACAM5 →	+1.168	+1.222	<.001	<.001	3	6
CCRCC	TSPAN13 →	+0.670	+0.172	.002	.002	3	6
BRCA	BCAS1 →	+1.458	+3.737	<.001	<.001	3	5
BRCA	AGR2 →	+1.163	+3.013	<.001	<.001	3	5
HNSC	ELAPOR1 →	+1.067	+1.840	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,533 associations by consensus.

FOXA1 vs FOXA1_S331 — OV

Explore this scatter interactively →