FOXA1

Across TCGA patient cohorts, FOXA1 protein abundance is significantly associated with the RNA expression of many other genes, with 10,724 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible FOXA1-associated genes across cancer lineages are CEACAM5, AGR2, and TTC6. Each is linked with FOXA1 in more than 3 cancer types. Because this analysis shows association rather than direction, both FOXA1-to-partner and partner-to-FOXA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FOXA1 versus CEACAM5 in LSCC, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXA1→partner) and Y-score (partner→FOXA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CEACAM5 →	+2.142	+0.620	<.001	<.001	3	4
BRCA	AGR2 →	+3.852	+0.729	<.001	<.001	3	4
BRCA	TTC6 →	+2.250	+0.859	<.001	<.001	3	4
BRCA	TFF3 →	+4.284	+0.701	<.001	<.001	3	4
UCEC	LINC00517 →	+0.923	+0.809	<.001	<.001	3	4
HNSC	FAM83E →	+2.124	+1.179	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,724 associations by consensus.

FOXA1 vs CEACAM5 — LSCC

Explore this scatter interactively →