FOSL2

Across TCGA patient cohorts, FOSL2 mutation is significantly associated with the RNA expression of many other genes, with 215 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FOSL2-associated genes across cancer lineages are NATP, LINC01400, and RN7SL847P. Each is linked with FOSL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FOSL2-to-partner and partner-to-FOSL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NATP grouped by FOSL2-low versus FOSL2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FOSL2→partner) and Y-score (partner→FOSL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	NATP →	+0.010	+3.900	<.001	.008	3	2
HNSC	LINC01400 →	+0.220	+5.124	<.001	.008	3	2
CESC	RN7SL847P →	+0.229	+5.010	<.001	.009	3	2
SKCM	ITGAE →	+0.577	+2.591	.001	.006	3	2
UCEC	CIAO2B →	+0.531	+3.606	.002	.001	3	2
LUAD	SPANXN4 →	+0.538	+6.087	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 215 associations by consensus.

NATP by FOSL2 expression — SKCM

Explore this box plot interactively →