FOSL2

Across TCGA cell cohorts, FOSL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,611 significant associations in total. BONE shows the largest number of these associations.

The most reproducible FOSL2-associated GO terms across cancer lineages are Transforming growth factor beta1 production, Regulation of cell-matrix adhesion, and Regulation of cell-substrate junction assembly. Each is linked with FOSL2 in more than 16 cancer types. Because this analysis shows association rather than direction, both FOSL2-to-partner and partner-to-FOSL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transforming growth factor beta1 production grouped by FOSL2-low versus FOSL2-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FOSL2→partner) and Y-score (partner→FOSL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Transforming growth factor beta1 production →	+0.364	+2.477	<.001	<.001	3	17
BONE	Regulation of cell-matrix adhesion →	+0.149	+3.071	<.001	<.001	3	16
BONE	Regulation of cell-substrate junction assembly →	+0.169	+3.038	<.001	<.001	3	15
BONE	Regulation of focal adhesion assembly →	+0.169	+3.038	<.001	<.001	3	15
BONE	Transforming growth factor beta production →	+0.362	+2.967	<.001	<.001	3	14
BONE	Positive regulation of plasma membrane repair →	+0.322	+3.186	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,611 associations by consensus.

Transforming growth factor beta1 production by FOSL2 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →