FOSL1

Across TCGA cell cohorts, FOSL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,144 significant associations in total. BONE shows the largest number of these associations.

The most reproducible FOSL1-associated GO terms across cancer lineages are Urokinase plasminogen activator signaling pathway, Regulation of plasminogen activation, and Cellular response to external stimulus. Each is linked with FOSL1 in more than 18 cancer types. Because this analysis shows association rather than direction, both FOSL1-to-partner and partner-to-FOSL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Urokinase plasminogen activator signaling pathway grouped by FOSL1-low versus FOSL1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FOSL1→partner) and Y-score (partner→FOSL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Urokinase plasminogen activator signaling pathway →	+1.487	+4.018	<.001	<.001	3	19
BONE	Regulation of plasminogen activation →	+0.297	+3.911	<.001	<.001	3	17
BONE	Cellular response to external stimulus →	+0.095	+4.389	<.001	<.001	3	16
BONE	Fibrinolysis →	+1.905	+4.178	<.001	<.001	3	16
CNS	Regulation of hemostasis →	+0.222	+3.070	<.001	<.001	3	15
BONE	Regulation of coagulation →	+0.191	+4.753	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,144 associations by consensus.

Urokinase plasminogen activator signaling pathway by FOSL1 expression — BREAST

Explore this box plot interactively →