FOSB

Across TCGA patient cohorts, FOSB protein abundance is significantly associated with the RNA expression of many other genes, with 3,680 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible FOSB-associated genes across cancer lineages are SNX15, VWF, and EGR1. Each is linked with FOSB in more than 1 cancer types. Because this analysis shows association rather than direction, both FOSB-to-partner and partner-to-FOSB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FOSB versus SNX15 in HNSC, with a Pearson correlation of -0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FOSB→partner) and Y-score (partner→FOSB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SNX15 →	-0.342	-0.764	.004	<.001	3	2
LSCC	VWF →	+0.684	+0.487	<.001	.001	3	2
LSCC	EGR1 →	+0.813	+0.420	.001	.002	3	2
LUAD	NR4A1 →	+1.099	+0.716	.006	.004	3	2
LUAD	CSRNP1 →	+0.882	+0.760	.003	.005	3	2
LUAD	NFIL3 →	+0.569	+0.589	.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,680 associations by consensus.

FOSB vs SNX15 — HNSC

Explore this scatter interactively →