FOSB

Across TCGA cell cohorts, FOSB RNA expression is significantly associated with the go_rna of many other GO terms, with 2,840 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible FOSB-associated GO terms across cancer lineages are Cellular response to parathyroid hormone stimulus, Response to interleukin-8, and Cellular response to interleukin-8. Each is linked with FOSB in more than 18 cancer types. Because this analysis shows association rather than direction, both FOSB-to-partner and partner-to-FOSB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to parathyroid hormone stimulus grouped by FOSB-low versus FOSB-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FOSB→partner) and Y-score (partner→FOSB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Cellular response to parathyroid hormone stimulus →	+1.403	+2.080	<.001	<.001	3	19
LUNG_NSCLC_LUSC	Response to interleukin-8 →	+1.724	+4.038	<.001	<.001	3	19
LUNG_NSCLC_LUSC	Cellular response to interleukin-8 →	+1.724	+4.038	<.001	<.001	3	19
KIDNEY	Response to prolactin →	+1.281	+4.085	<.001	<.001	3	19
LUNG_SCLC	Response to zinc ion starvation →	+0.449	+2.404	<.001	<.001	3	18
URINARY_TRACT	Skeletal muscle cell proliferation →	+1.506	+4.590	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,840 associations by consensus.

Cellular response to parathyroid hormone stimulus by FOSB expression — LUNG_SCLC

Explore this box plot interactively →