FOS

Across TCGA cell cohorts, FOS RNA expression is significantly associated with the go_rna of many other GO terms, with 3,330 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FOS-associated GO terms across cancer lineages are Response to zinc ion starvation, Response to prolactin, and Cellular response to zinc ion starvation. Each is linked with FOS in more than 19 cancer types. Because this analysis shows association rather than direction, both FOS-to-partner and partner-to-FOS results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to zinc ion starvation grouped by FOS-low versus FOS-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FOS→partner) and Y-score (partner→FOS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Response to zinc ion starvation →	+0.467	+3.603	<.001	<.001	3	20
LUNG_NSCLC_LUSC	Response to prolactin →	+1.128	+5.479	.002	<.001	3	20
LUNG_SCLC	Cellular response to zinc ion starvation →	+0.467	+3.603	<.001	<.001	3	20
LIVER	Response to metal ion starvation →	+0.298	+4.268	<.001	<.001	3	19
LUNG_SCLC	Response to interleukin-8 →	+1.619	+3.460	<.001	<.001	3	19
LUNG_SCLC	Cellular response to interleukin-8 →	+1.619	+3.460	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,330 associations by consensus.

Response to zinc ion starvation by FOS expression — LUNG_SCLC

Explore this box plot interactively →