FOLR1

Across TCGA pan-cancer cohorts, FOLR1 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated FOLR1 data layer compared with 25 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher FOLR1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated FOLR1 expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

HNSC and LSCC are the cancer types where FOLR1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	All	0.893	0.645	.005	15	view →
LSCC	DFS	Tertile	All	0.926	1.000	.013	4	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

FOLR1–HNSC (DFS)

Open the HNSC breakdown →