Across TCGA patient cohorts, FOCAD RNA expression is significantly associated with the protein abundance of many other proteins, with 9,215 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible FOCAD-associated proteins across cancer lineages are MTAP, PLAA, and MLLT3. Each is linked with FOCAD in more than 5 cancer types. Because this analysis shows association rather than direction, both FOCAD-to-partner and partner-to-FOCAD results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FOCAD→partner) and Y-score (partner→FOCAD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MTAP →	+0.562	+0.815	<.001	<.001	3	6
GBM	PLAA →	+0.561	+0.848	<.001	.001	3	5
LSCC	MLLT3 →	+0.417	+0.596	.004	.004	3	4
BRCA	ESF1 →	-0.344	-0.660	<.001	<.001	3	4
GBM	TTC37 →	+0.310	+0.730	.001	.001	3	4
PDAC	WDR61 →	+0.289	+0.327	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,215 associations by consensus.

Exploration

FOCAD survival (RNA) · tumor vs normal (RNA) · all FOCAD data types