Across TCGA pan-cancer cohorts, FOCAD-AS1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated FOCAD-AS1 data layer.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher FOCAD-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated FOCAD-AS1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and THYM show a favorable association.

LUAD, KICH, and UCS are the cancer types where FOCAD-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Tertile	All	0.781	0.601	.002	77	view →
KICH	DFS	Quartile	III,IV	0.131	1.000	.002	62	view →
UCS	OS	Median	All	0.221	0.512	.004	38	view →
THYM	DFS	Median	All	0.880	0.633	.002	32	view →
LIHC	OS	Median	III,IV	0.445	0.741	.007	31	view →
MESO	DFS	Tertile	III,IV	0.158	0.836	.002	30	view →
KIRC	DFS	Median	IV	0.387	0.632	.015	28	view →
UCEC	DFS	Tertile	IV	0.310	0.680	.012	28	view →
COAD	DFS	Tertile	III,IV	0.123	0.673	<.001	26	view →
BLCA	DFS	Tertile	IV	0.211	0.601	.002	24	view →
OV	DFS	Median	III,IV	0.415	0.329	.002	20	view →
UVM	OS	Median	III,IV	0.638	0.947	.004	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

Exploration

Same gene, other analysis: FOCAD-AS1 tumor-vs-normal RNA expression · all FOCAD-AS1 data types