FNTB

Across TCGA patient cohorts, FNTB protein abundance is significantly associated with the RNA expression of many other genes, with 5,239 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible FNTB-associated genes across cancer lineages are CINP, AP4S1, and GMPR2. Each is linked with FNTB in more than 3 cancer types. Because this analysis shows association rather than direction, both FNTB-to-partner and partner-to-FNTB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FNTB versus CINP in CCRCC, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FNTB→partner) and Y-score (partner→FNTB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	CINP →	+0.375	+0.284	<.001	.001	3	4
OV	AP4S1 →	+0.442	+0.268	<.001	.005	3	3
LSCC	GMPR2 →	+0.402	+0.276	<.001	<.001	3	3
LSCC	RNF170 →	+0.500	+0.231	.001	.001	3	3
BRCA	ACTR10 →	+0.251	+0.239	.005	<.001	3	3
BRCA	CDH11 →	+1.113	+0.242	.001	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,239 associations by consensus.

FNTB vs CINP — CCRCC

Explore this scatter interactively →